For the past 15 years, Shahin Nasr, PhD, hasĀ studied the visual system of humans andĀ non-human primates using a variety of techniques, from psychophysics andĀ event-related potentials (ERP) to conventional and high-resolution functionalĀ MRI, in order to understand the neural mechanisms underlying ...
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White Matter Changes Could Predict Cognitive Decline in Alzheimerās Disease
Alzheimerās disease is diagnosed based on abnormal pathology of two proteins in the brain: amyloid and tau. Research suggests, however, that other factors may also play a role. In a paper published online this week in the journal Neurology, a team of investigators at the Athinoula A. Martinos Cen...
Matt Rosen and Colleaguesā Journey Through the Secret Life of Plants
In the waning months of 1979, the legendary Motown artist Stevie Wonder released an album called Stevie Wonderās Journey Through "The Secret Life of Plants," the soundtrack to the documentary film The Secret Life of Plants. Equal parts frustrating and strangely compelling, and notably using some ...
With New PET Probe, Researchers Image Fibrosis of the Lungs
The MGH Martinos Center's Pauline DĆ©sogĆØre and colleagues have described a new positron emission tomography (PET) probe that canĀ help to advanceĀ noninvasive diagnosis of pulmonary fibrosis. Reported in a Science Translational MedicineĀ paper published onlineĀ today, the probe enables detection and ...
Nanodiamond-enhanced MRI: A Dazzling New Approach to Imaging
Nanodiamonds ā synthetic industrial diamonds only a few nanometers in size ā have recently attracted considerable attention because of the potential they offer for the targeted delivery of vaccines and cancer drugs as well asĀ for other uses. Thus far, options for imaging nanodiamonds have been li...
Jason Stockmann
Jason Stockmann, PhD, is broadly interested in magnetic resonance imaging hardware andĀ acquisition methods for improving data quality for both structural andĀ functional imaging. He has worked on diverse MRI scanners ranging in fieldĀ strength by two orders of magnitude, from low-field (80 mT) to u...
A New Role for Diffusion MRI in Treating Anxiety and Depression
Anxiety disorders and depression are widespread among adolescents in the U.S., affecting as many as one in four 13 to 18 year olds. Determining the best course of treatment can be difficult, though, as we still donāt fully understand the biology underlying them. Now, using cutting-edge brain i...
Deep Learning Offers Quantitative Means of Monitoring Disease Progression in Retinopathy of Prematurity
Retinopathy of prematurity (ROP) is an eye disorder affecting roughly two-thirds of premature infants weighing less than 250 g at birth and one of the leading causes of childhood blindness worldwide. Historically, clinical diagnosis of ROP has been subjective, resulting in considerable variabilit...
Ken Kwong and the Introduction of Noninvasive fMRI
In the early months of 1992 the neuroscience community was flush with excitement. Jack Belliveau, a graduate student with the MGH-NMR Center (now the MGH Martinos Center for Biomedical Imaging), had recently published in ScienceĀ his pioneering work with functional MRI, and the possibilities of th...
Understanding Eye-contact Avoidance in People With Autism
Individuals with autism spectrum disorder (ASD) often have difficulty looking others in the eyes. This is typically interpreted as a sign of social and personal indifference, but self-reports from people with autism suggests otherwise. Many say that looking others in the eye is uncomfortable or s...
Advanced MRI of Spinal Cord Function Could Provide Important Information for the Treatment of Multiple Sclerosis
A team of investigators at the MGH Martinos Center for Biomedical Imaging and Vanderbilt University Medical Center has reported a new approach to measuring spinal cord function that could help in more accurately understanding the degree of spinal cord damage in relapsing-remitting multiple sclero...
Estimating Tumor Boundaries in Cancer Surgery With Fluorescence Lifetime Imaging
Cancer is the second leading cause of death in the United States, with an estimated 1,762,450 new cases diagnosed and 606,880 deaths in 2019 alone. While important advances have been made in the development of treatments for cancer, including surgery, a number of challenges remain. Not least: sur...
Robert Savoy
Dr. Savoy received his academic training in applied mathematics at MIT (BSĀ 1971; MS 1975) and experimental psychology at Harvard University (PhDĀ 1980). This period included 10 years of work at Polaroid CorporationāsĀ Vision Research Laboratory, after which he joined the newly formed RowlandĀ Instit...
Publications Updates
May 11, 2020 The presubiculum links incipient amyloid and tau pathology to memory function in older persons Jacobs HIL, Augustinack JC, Schultz AP, Hanseeuw BJ, Locascio J, Amariglio RE, Papp KV, Rentz DM, Sperling RA, Johnson KA. Neurology. 2020 May 5;94(18):e1916-e1928. doi: 10.1212/WNL.00...
Meher Juttukonda
Dr. JuttukondaāsĀ research interests are in studying the balance between hemodynamic and metabolic function in the human brain as well as in the translation ofĀ these methods for characterizing microvascular health in cerebrovascularĀ diseases. A principal objective of his work has been to develop q...
New Software Improves Ability to Determine the Cause of Stroke
Determining the cause of an ischemic stroke is critical to preventing a second oneĀ and is a primary focus in the evaluation of stroke patients. But for all theĀ importance of identifying the cause, physicians have long lacked a robust and objective means to doĀ so. Now a team of investigators at...